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anti cd40l  (Bio X Cell)


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    Bio X Cell anti cd40l
    (A) Experimental schematic for B-C . (B) Plot shows the percentage of GC B cells of B220+ cells in mice pre-infused with 3BNC117 IgG2a in concert <t>with</t> <t>anti-CD40L</t> (maroon, for B-C ) or isotype control (pink, for B-C ). (C) Plot shows the percentage of PBs in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L or isotype control. (D) Experimental schematic for E-J . (E) Plot shows the percentage of GC B cells of B220+ cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a (+Ab, pink, for E-J ) or no antibody (control, -Ab, grey, for E-J ). (F) Plot shows the number of GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (G) Plot shows the percentage of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (H) Plot shows the number of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (I) Plot shows the percentage of TM4-Core+ cells of GC B cells in Cr2 KO mice pre- infused with 3BNC117 IgG2a or control. (J) Plot shows the number of TM4-Core+ GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. Data is displayed as mean ± SD. Each point represents a single mouse from at least two independent experiments. Statistical significance for B-C was determined using two-tailed unpaired t tests with Welch’s correction. Statistical significance for E-J was determined using two-tailed Mann-Whitney U tests. ns denotes non-significant, * denotes p ≤ 0.05, ** denotes p ≤ 0.01 and **** denotes p ≤ 0.0001.
    Anti Cd40l, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 95/100, based on 179 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/invivomab+anti+mouse+cd40l/InVivoMAb+anti-mouse+CD40L/bio_rxiv__64898__2026__03__27__714269-137-0-3
    Average 95 stars, based on 179 article reviews
    anti cd40l - by Bioz Stars, 2026-10
    95/100 stars

    Images

    1) Product Images from "Fc receptor dependent and independent mechanisms of antibody-mediated enhancement of immune responses"

    Article Title: Fc receptor dependent and independent mechanisms of antibody-mediated enhancement of immune responses

    Journal: bioRxiv

    doi: 10.64898/2026.03.27.714269

    (A) Experimental schematic for B-C . (B) Plot shows the percentage of GC B cells of B220+ cells in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L (maroon, for B-C ) or isotype control (pink, for B-C ). (C) Plot shows the percentage of PBs in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L or isotype control. (D) Experimental schematic for E-J . (E) Plot shows the percentage of GC B cells of B220+ cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a (+Ab, pink, for E-J ) or no antibody (control, -Ab, grey, for E-J ). (F) Plot shows the number of GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (G) Plot shows the percentage of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (H) Plot shows the number of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (I) Plot shows the percentage of TM4-Core+ cells of GC B cells in Cr2 KO mice pre- infused with 3BNC117 IgG2a or control. (J) Plot shows the number of TM4-Core+ GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. Data is displayed as mean ± SD. Each point represents a single mouse from at least two independent experiments. Statistical significance for B-C was determined using two-tailed unpaired t tests with Welch’s correction. Statistical significance for E-J was determined using two-tailed Mann-Whitney U tests. ns denotes non-significant, * denotes p ≤ 0.05, ** denotes p ≤ 0.01 and **** denotes p ≤ 0.0001.
    Figure Legend Snippet: (A) Experimental schematic for B-C . (B) Plot shows the percentage of GC B cells of B220+ cells in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L (maroon, for B-C ) or isotype control (pink, for B-C ). (C) Plot shows the percentage of PBs in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L or isotype control. (D) Experimental schematic for E-J . (E) Plot shows the percentage of GC B cells of B220+ cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a (+Ab, pink, for E-J ) or no antibody (control, -Ab, grey, for E-J ). (F) Plot shows the number of GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (G) Plot shows the percentage of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (H) Plot shows the number of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (I) Plot shows the percentage of TM4-Core+ cells of GC B cells in Cr2 KO mice pre- infused with 3BNC117 IgG2a or control. (J) Plot shows the number of TM4-Core+ GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. Data is displayed as mean ± SD. Each point represents a single mouse from at least two independent experiments. Statistical significance for B-C was determined using two-tailed unpaired t tests with Welch’s correction. Statistical significance for E-J was determined using two-tailed Mann-Whitney U tests. ns denotes non-significant, * denotes p ≤ 0.05, ** denotes p ≤ 0.01 and **** denotes p ≤ 0.0001.

    Techniques Used: Control, Two Tailed Test, MANN-WHITNEY

    Related Articles

    Transplantation Assay:

    Article Title: Combined abdominal heterotopic heart and aorta transplant model in mice
    Article Snippet: .. For a subset of additional transplants, the long-term viability of this combined aorta and heart transplant model were tested in syngraft (C57Bl/6 to C57Bl/6) (n = 3) and allograft (Balb/c to C57Bl/6) models (n = 3), with the administration of 250 μg of InVivoMab anti-mouse CD40L (CD154; clone MR-1; Bio X Cell, West Lebanon, NH) on the day of transplantation, and 200 μg of InVivoMab recombinant CTLA-4-Ig (hum/hum; Bio X Cell) on day 2 post-transplantation [ , ]. .. Four representative sections from each aortic and heart graft were stained with hematoxylin and eosin (H&E; Leica Biosystems, Buffalo Grove, IL) or Movat’s pentachrome (Newcomer Supply, Middleton, WI) and digital images were captured using an Olympus BX61 microscope (Center Valley, PA).

    Recombinant:

    Article Title: Combined abdominal heterotopic heart and aorta transplant model in mice
    Article Snippet: .. For a subset of additional transplants, the long-term viability of this combined aorta and heart transplant model were tested in syngraft (C57Bl/6 to C57Bl/6) (n = 3) and allograft (Balb/c to C57Bl/6) models (n = 3), with the administration of 250 μg of InVivoMab anti-mouse CD40L (CD154; clone MR-1; Bio X Cell, West Lebanon, NH) on the day of transplantation, and 200 μg of InVivoMab recombinant CTLA-4-Ig (hum/hum; Bio X Cell) on day 2 post-transplantation [ , ]. .. Four representative sections from each aortic and heart graft were stained with hematoxylin and eosin (H&E; Leica Biosystems, Buffalo Grove, IL) or Movat’s pentachrome (Newcomer Supply, Middleton, WI) and digital images were captured using an Olympus BX61 microscope (Center Valley, PA).

    other:

    Article Title: Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma
    Article Snippet: InVivoMAb anti-mouse CD40L (clone MR1) , BioXcell , Cat:BE0017-1; RRID: AB_1107601.



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    (A) Experimental schematic for B-C . (B) Plot shows the percentage of GC B cells of B220+ cells in mice pre-infused with 3BNC117 IgG2a in concert <t>with</t> <t>anti-CD40L</t> (maroon, for B-C ) or isotype control (pink, for B-C ). (C) Plot shows the percentage of PBs in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L or isotype control. (D) Experimental schematic for E-J . (E) Plot shows the percentage of GC B cells of B220+ cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a (+Ab, pink, for E-J ) or no antibody (control, -Ab, grey, for E-J ). (F) Plot shows the number of GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (G) Plot shows the percentage of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (H) Plot shows the number of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (I) Plot shows the percentage of TM4-Core+ cells of GC B cells in Cr2 KO mice pre- infused with 3BNC117 IgG2a or control. (J) Plot shows the number of TM4-Core+ GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. Data is displayed as mean ± SD. Each point represents a single mouse from at least two independent experiments. Statistical significance for B-C was determined using two-tailed unpaired t tests with Welch’s correction. Statistical significance for E-J was determined using two-tailed Mann-Whitney U tests. ns denotes non-significant, * denotes p ≤ 0.05, ** denotes p ≤ 0.01 and **** denotes p ≤ 0.0001.
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    (A) Experimental schematic for B-C . (B) Plot shows the percentage of GC B cells of B220+ cells in mice pre-infused with 3BNC117 IgG2a in concert <t>with</t> <t>anti-CD40L</t> (maroon, for B-C ) or isotype control (pink, for B-C ). (C) Plot shows the percentage of PBs in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L or isotype control. (D) Experimental schematic for E-J . (E) Plot shows the percentage of GC B cells of B220+ cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a (+Ab, pink, for E-J ) or no antibody (control, -Ab, grey, for E-J ). (F) Plot shows the number of GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (G) Plot shows the percentage of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (H) Plot shows the number of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (I) Plot shows the percentage of TM4-Core+ cells of GC B cells in Cr2 KO mice pre- infused with 3BNC117 IgG2a or control. (J) Plot shows the number of TM4-Core+ GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. Data is displayed as mean ± SD. Each point represents a single mouse from at least two independent experiments. Statistical significance for B-C was determined using two-tailed unpaired t tests with Welch’s correction. Statistical significance for E-J was determined using two-tailed Mann-Whitney U tests. ns denotes non-significant, * denotes p ≤ 0.05, ** denotes p ≤ 0.01 and **** denotes p ≤ 0.0001.
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    Image Search Results


    (A) Experimental schematic for B-C . (B) Plot shows the percentage of GC B cells of B220+ cells in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L (maroon, for B-C ) or isotype control (pink, for B-C ). (C) Plot shows the percentage of PBs in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L or isotype control. (D) Experimental schematic for E-J . (E) Plot shows the percentage of GC B cells of B220+ cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a (+Ab, pink, for E-J ) or no antibody (control, -Ab, grey, for E-J ). (F) Plot shows the number of GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (G) Plot shows the percentage of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (H) Plot shows the number of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (I) Plot shows the percentage of TM4-Core+ cells of GC B cells in Cr2 KO mice pre- infused with 3BNC117 IgG2a or control. (J) Plot shows the number of TM4-Core+ GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. Data is displayed as mean ± SD. Each point represents a single mouse from at least two independent experiments. Statistical significance for B-C was determined using two-tailed unpaired t tests with Welch’s correction. Statistical significance for E-J was determined using two-tailed Mann-Whitney U tests. ns denotes non-significant, * denotes p ≤ 0.05, ** denotes p ≤ 0.01 and **** denotes p ≤ 0.0001.

    Journal: bioRxiv

    Article Title: Fc receptor dependent and independent mechanisms of antibody-mediated enhancement of immune responses

    doi: 10.64898/2026.03.27.714269

    Figure Lengend Snippet: (A) Experimental schematic for B-C . (B) Plot shows the percentage of GC B cells of B220+ cells in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L (maroon, for B-C ) or isotype control (pink, for B-C ). (C) Plot shows the percentage of PBs in mice pre-infused with 3BNC117 IgG2a in concert with anti-CD40L or isotype control. (D) Experimental schematic for E-J . (E) Plot shows the percentage of GC B cells of B220+ cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a (+Ab, pink, for E-J ) or no antibody (control, -Ab, grey, for E-J ). (F) Plot shows the number of GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (G) Plot shows the percentage of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (H) Plot shows the number of PBs in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. (I) Plot shows the percentage of TM4-Core+ cells of GC B cells in Cr2 KO mice pre- infused with 3BNC117 IgG2a or control. (J) Plot shows the number of TM4-Core+ GC B cells in Cr2 KO mice pre-infused with 3BNC117 IgG2a or control. Data is displayed as mean ± SD. Each point represents a single mouse from at least two independent experiments. Statistical significance for B-C was determined using two-tailed unpaired t tests with Welch’s correction. Statistical significance for E-J was determined using two-tailed Mann-Whitney U tests. ns denotes non-significant, * denotes p ≤ 0.05, ** denotes p ≤ 0.01 and **** denotes p ≤ 0.0001.

    Article Snippet: Anti-CD40L (Clone: MR1, BioXCell BE0017-1) and the armenian hamster isotype control (BioXCell BE0091) were purchased from BioXCell.

    Techniques: Control, Two Tailed Test, MANN-WHITNEY

    Left lungs from 3T-FVB mice are transplanted into C57Bl/6 recipient mice and treated with CD40L Ab and CTLA4Ig on POD 0 and POD 2, respectively, to induce allograft tolerance. Doxycycline ingestion from post-operative day (POD) 7 to POD 9.5 induces club cell injury that triggers CLAD by POD 16. Recipients that do not ingest Doxycycline remain tolerant to their allografts.

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    Article Title: Molecular Imaging of the TGF-β Activating Integrin αvβ6 Detects Chronic Lung Allograft Dysfunction

    doi: 10.64898/2026.01.07.698265

    Figure Lengend Snippet: Left lungs from 3T-FVB mice are transplanted into C57Bl/6 recipient mice and treated with CD40L Ab and CTLA4Ig on POD 0 and POD 2, respectively, to induce allograft tolerance. Doxycycline ingestion from post-operative day (POD) 7 to POD 9.5 induces club cell injury that triggers CLAD by POD 16. Recipients that do not ingest Doxycycline remain tolerant to their allografts.

    Article Snippet: To induce allograft acceptance, recipients received intraperitoneal (i.p.) injections of CD40L Abs (250 μg; clone MR1, Bio-X-Cell) on POD 0 and human recombinant CTLA4 Ig (200 μg; Bio-X-Cell) on POD 2.

    Techniques: